Haffkine's vaccine made in a makeshift room
Sent to Bombay in October 1896 after plague broke out in the Mandvi dock district, bacteriologist Waldemar Haffkine worked with a few assistants in a cramped improvised laboratory at Grant Medical College. Within about three months he had produced a heat-killed plague vaccine. In January 1897 he injected himself with it before running trials, including one among inmates of Byculla jail, where the vaccinated prisoners showed markedly fewer plague cases and deaths than the unvaccinated.