Love as the force evil cannot copy
Meg defeats IT not with cleverness but by loving her brother, something the controlling intelligence cannot feel or replicate. The story asserts love as the one power beyond totalitarian control.
A Wrinkle in Time: 50th Anniversary Commemorative Edition
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Tesseract: folding space to skip distance
A tesseract (a 'wrinkle') is travel by folding the fabric of space so two distant points touch, the way an ant can cross a pinched fold of cloth instead of walking its full length. Distance becomes a matter of the shape of space, not of speed. The book uses this to present higher dimensions as something intuitive rather than abstract.
Enforced sameness is the signature of evil
On Camazotz every child bounces a ball in the same rhythm and a child who falls out of step is punished, and IT presents this total uniformity as peace and the removal of suffering. The book argues that evil advances by offering relief from the burden of choice and difference. Accepting that relief means giving up the self.
Your flaws may be your weapons
Mrs Whatsit gives Meg her faults, her impatience, stubbornness and anger, as gifts for the fight rather than things she must get rid of first. Traits that make a person awkward in ordinary social life can be exactly what resists a system built on smooth compliance. Seen this way, a supposed defect is a capacity that simply hasn't found its use yet.
Meg rescues Charles Wallace through love
On the planet Camazotz, Charles Wallace, the most gifted of the Murry children, arrogantly believes his intellect can withstand IT, the disembodied brain that controls the planet. He is absorbed and turned into a mouthpiece for its conformist order.